Zimbabwe measles outbreak: Death toll tops 700, Vaccination drive ...



gamaleya vaccine :: Article Creator

Mysterious Death Of COVID Vaccine Creator Sparks Conspiracy Theories

A file photo of A healthcare worker administering a dose of Russia's Sputnik V Covid-19 vaccine to a patient at a vaccination centre in the GUM State Department store in Moscow on October 21, 2021 © DIMITAR DILKOFF/AFP/Getty Images A file photo of A healthcare worker administering a dose of Russia's Sputnik V Covid-19 vaccine to a patient at a vaccination centre in the GUM State Department store in Moscow on October 21, 2021

The death of a Russian virologist who helped develop the country's COVID vaccine has sparked conspiracy theories online about the nature of his demise.

Andrey Botikov, one of 18 scientists who developed the Sputnik V vaccine at the Gamaleya National Research Center, was strangled in his Rogova Street home on March 2, Russian news outlet Regnum reported, citing official sources.

While official accounts point towards a domestic altercation, the 47-year-old's death comes amid a string of members of the Russian elite being found dead in mysterious circumstances over the past year, including scientists and businessmen.

The Investigative Committee of Russia (ICR) announced on Friday that it had opened a murder investigation, believing that a 29-year-old man strangled the scientist with a belt during a disagreement before fleeing the scene.

The ICR's Moscow division didn't name Botikov in a statement, but said investigators had identified and located the assailant "in the shortest possible time."

"During the interrogation, he admitted his guilt, he was charged," it added. "Previously, the defendant was prosecuted for committing a serious crime."

The ICR didn't respond to a request by Newsweek about the identification of the victim. It hasn't provided a public update since March 3.

While many reacting to the story on social media suggested that his death may have been premeditated, others jumped on the story to claim he had died as a result of his own vaccine, or because he was planning to speak out about it.

"Was he about to reveal the truth?" Matt Wallace, a crypto influencer, wrote in a tweet that has since been viewed 2.4 million times and received nearly 10,000 retweets.

Meanwhile, WSPN Speculation News claimed Botikov "was shot up with over 40 doses [of the COVID vaccine] in his apartment in northwest Moscow, he is dead but reports say he died covid free!"

"Reportedly he had one too many up his..." wrote Per Ekstrom, above an image of the Sputnik V vaccine.

"Totally normal that Andrey Botikov, the guy who created the first COVID vaax [sic], was found strangled to death," Insurrectionist Barbie, a pejorative term for women with conservative views, tweeted. "Especially in light of everything that is coming out about both the vaax [sic] and the origins of the virus. Nothing to see here."

Last week, FBI director Christopher Wray said that the agency believed it "most likely" that COVID emerged into the human population from a mishap in a Chinese lab. It followed a report that the U.S. Department of Energy had adopted this belief in light of new intelligence.

Botikov worked as a virologist at the Gamaleya National Research Center since 2014, and was part of the team responsible for the nation's vaccine—which Russia claimed had an efficacy at clinical trials of 91 percent, far higher than other vaccines.

However, Russia has faced vaccine hesitancy domestically. Just over 60 percent of Russians have received at least one dose, according to the latest figures by Johns Hopkins University.

Its sales on the international market have been damaged by the rushed vaccine trials and slowness with sharing scientific results with the international community, researchers at the Carnegie Endowment for International Peace have said.

Botikov's apparent death comes just over two weeks after that of Major General Vladimir Makarov, a high-ranking Russian military official who state investigators said took his own life after being relieved of duty.

In late November, the Russian Embassy in Paris confirmed the death of Vyacheslav Taran, a Russian billionaire and founder of Forex Club, in a helicopter crash near his home in southeastern France.

The former head of the Moscow Aviation Institute, Anatoly Gerashchenko, died last year after falling down "several flights of stairs."

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Global "Covid-19 Vaccine Market" Highlights 2023-2031: Best Growth Survey

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1 Covid-19 Vaccine Market Overview1.1 Product Overview and Scope of Covid-19 Vaccine Market1.2 Covid-19 Vaccine Market Segment by Type1.2.1 Global Covid-19 Vaccine Market Sales and CAGR (Percent) Comparison by Type (2017-2031)1.3 Global Covid-19 Vaccine Market Segment by Application1.3.1 Covid-19 Vaccine Market Consumption (Sales) Comparison by Application (2017-2031)1.4 Global Covid-19 Vaccine Market, Region Wise (2017-2031)1.4.1 Global Covid-19 Vaccine Market Size (Revenue) and CAGR (Percent) Comparison by Region (2017-2031)1.4.2 United States Covid-19 Vaccine Market Status and Prospect (2017-2031)1.4.3 Europe Covid-19 Vaccine Market Status and Prospect (2017-2031)1.4.4 China Covid-19 Vaccine Market Status and Prospect (2017-2031)1.4.5 Japan Covid-19 Vaccine Market Status and Prospect (2017-2031)1.4.6 India Covid-19 Vaccine Market Status and Prospect (2017-2031)1.4.7 Southeast Asia Covid-19 Vaccine Market Status and Prospect (2017-2031)1.4.8 Latin America Covid-19 Vaccine Market Status and Prospect (2017-2031)1.4.9 Middle East and Africa Covid-19 Vaccine Market Status and Prospect (2017-2031)1.5 Global Market Size (Revenue) of Covid-19 Vaccines (2017-2031)1.5.1 Global Covid-19 Vaccine Market Revenue Status and Outlook (2017-2031)1.5.2 Global Covid-19 Vaccine Market Sales Status and Outlook (2017-2031)1.6 Influence of Regional Conflicts on the Covid-19 Vaccine Industry1.7 Impact of Carbon Neutrality on the Covid-19 Vaccine Industry

2 Covid-19 Vaccine Market Upstream and Downstream Analysis2.1 Covid-19 Vaccine Industrial Chain Analysis2.2 Key Raw Materials Suppliers and Price Analysis2.3 Key Raw Materials Supply and Demand Analysis2.4 Market Concentration Rate of Raw Materials2.5 Manufacturing Process Analysis2.6 Manufacturing Cost Structure Analysis2.6.1 Labor Cost Analysis2.6.2 Energy Costs Analysis2.6.3 RandD Costs Analysis2.7 Major Downstream Buyers of Covid-19 Vaccine Analysis2.8 Impact of COVID-19 on the Industry Upstream and Downstream

3 Players Profiles4 Global Covid-19 Vaccine Market Landscape by Player4.1 Global Covid-19 Vaccine Sales and Share by Player (2017-2022)4.2 Global Covid-19 Vaccine Revenue and Market Share by Player (2017-2022)4.3 Global Covid-19 Vaccine Average Price by Player (2017-2022)4.4 Global Covid-19 Vaccine Gross Margin by Player (2017-2022)4.5 Covid-19 Vaccine Market Competitive Situation and Trends4.5.1 Covid-19 Vaccine Market Concentration Rate4.5.2 Covid-19 Vaccine Market Share of Top 3 and Top 6 Players4.5.3 Mergers and Acquisitions, Expansion

5 Global Covid-19 Vaccine Sales, Revenue, Price Trend by Type5.1 Global Covid-19 Vaccine Sales and Market Share by Type (2017-2022)5.2 Global Covid-19 Vaccine Revenue and Market Share by Type (2017-2022)5.3 Global Covid-19 Vaccine Price by Type (2017-2022)5.4 Global Covid-19 Vaccine Sales, Revenue and Growth Rate by Type (2017-2022)

6 Global Covid-19 Vaccine Market Analysis by Application6.1 Global Covid-19 Vaccine Consumption and Market Share by Application (2017-2022)6.2 Global Covid-19 Vaccine Consumption Revenue and Market Share by Application (2017-2022)6.3 Global Covid-19 Vaccine Consumption and Growth Rate by Application (2017-2022)

7 Global Covid-19 Vaccine Sales and Revenue Region Wise (2017-2022)7.1 Global Covid-19 Vaccine Sales and Market Share, Region Wise (2017-2022)7.2 Global Covid-19 Vaccine Revenue and Market Share, Region Wise (2017-2022)7.3 Global Covid-19 Vaccine Sales, Revenue, Price and Gross Margin (2017-2022)7.4 United States Covid-19 Vaccine Sales, Revenue, Price and Gross Margin (2017-2022)7.5 Europe Covid-19 Vaccine Sales, Revenue, Price and Gross Margin (2017-2022)7.6 China Covid-19 Vaccine Sales, Revenue, Price and Gross Margin (2017-2022)7.7 Japan Covid-19 Vaccine Sales, Revenue, Price and Gross Margin (2017-2022)7.8 India Covid-19 Vaccine Sales, Revenue, Price and Gross Margin (2017-2022)7.9 Southeast Asia Covid-19 Vaccine Sales, Revenue, Price and Gross Margin (2017-2022)7.10 Latin America Covid-19 Vaccine Sales, Revenue, Price and Gross Margin (2017-2022)7.11 Middle East and Africa Covid-19 Vaccine Sales, Revenue, Price and Gross Margin (2017-2022)

8 Global Covid-19 Vaccine Market Forecast (2022-2031)8.1 Global Covid-19 Vaccine Sales, Revenue Forecast (2022-2031)8.1.1 Global Covid-19 Vaccine Sales and Growth Rate Forecast (2022-2031)8.1.2 Global Covid-19 Vaccine Revenue and Growth Rate Forecast (2022-2031)8.1.3 Global Covid-19 Vaccine Price and Trend Forecast (2022-2031)8.2 Global Covid-19 Vaccine Sales and Revenue Forecast, Region Wise (2022-2031)8.2.1 United States Covid-19 Vaccine Sales and Revenue Forecast (2022-2031)8.2.2 Europe Covid-19 Vaccine Sales and Revenue Forecast (2022-2031)8.2.3 China Covid-19 Vaccine Sales and Revenue Forecast (2022-2031)8.2.4 Japan Covid-19 Vaccine Sales and Revenue Forecast (2022-2031)8.2.5 India Covid-19 Vaccine Sales and Revenue Forecast (2022-2031)8.2.6 Southeast Asia Covid-19 Vaccine Sales and Revenue Forecast (2022-2031)8.2.7 Latin America Covid-19 Vaccine Sales and Revenue Forecast (2022-2031)8.2.8 Middle East and Africa Covid-19 Vaccine Sales and Revenue Forecast (2022-2031)8.3 Global Covid-19 Vaccine Sales, Revenue and Price Forecast by Type (2022-2031)8.4 Global Covid-19 Vaccine Consumption Forecast by Application (2022-2031)8.5 Covid-19 Vaccine Market Forecast Under COVID-19

9 Industry Outlook9.1 Covid-19 Vaccine Market Drivers Analysis9.2 Covid-19 Vaccine Market Restraints and Challenges9.3 Covid-19 Vaccine Market Opportunities Analysis9.4 Emerging Market Trends9.5 Covid-19 Vaccine Industry Technology Status and Trends9.6 News of Product Release9.7 Consumer Preference Analysis9.8 Covid-19 Vaccine Industry Development Trends under COVID-19 Outbreak9.8.1 Global COVID-19 Status Overview9.8.2 Influence of COVID-19 Outbreak on Covid-19 Vaccine Industry Development

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Promising New Malaria Vaccine Has Been Approved In Two Countries, With Others Likely To Follow

Ghana and Nigeria both approved a new malaria vaccine this month — an important step in the fight against a disease that kills more than 600,000 people annually.

At least 10 other African countries are reviewing trial data for the shot, according to the World Health Organization, so more approvals are expected in the coming weeks.

The vaccine, developed by researchers at Oxford University, is the second to become publicly available. The first, a shot called Mosquirix from drugmaker GSK, has been administered through a pilot program in Kenya, Ghana and Malawi since 2019 but is still in limited supply.

The new vaccine is the first malaria shot to be approved in Nigeria, whose deaths from the disease make up 31% of the worldwide total.

"It's good news," said Dyann Wirth, an infectious diseases professor at the Harvard T.H. Chan School of Public Health, adding, "These vaccines can save lives and save hospitalizations, reduce the impact of the disease in the most vulnerable young children."

An estimated 619,000 people died of malaria in 2021, the latest annual total available, and 96% of those deaths occurred in Africa, according to the WHO. The disease is caused by a parasite that spreads to humans through mosquito bites.

Scientists have been researching possible malaria vaccines since the 1960s; Mosquirix took more than 30 years to develop and test. To prevent infection, countries with high rates of malaria mostly rely on mosquito nets, insecticides or antimalarial drugs for children.

Next steps for the new malaria shot

The Oxford vaccine consists of three doses administered every four weeks, followed by a fourth dose a year later. So far, the only peer-reviewed data on it comes from a small trial of 450 infants up to 17 months old in Burkina Faso. Among that group, the shot was found to reduce the risk of malaria by 77%.

Adrian Hill, the vaccine's lead developer and co-director of the Oxford Martin Program on Vaccines, said a Phase 3 trial of 4,800 children up to 3 years old showed similar safety and efficacy. But those findings have not been published in a peer-reviewed journal.

The WHO is still evaluating data on the Oxford vaccine and has not yet recommended it for use. Countries without their own regulatory processes for approving vaccines often defer to the WHO's recommendations, Wirth said, so they may still wait for that.

The WHO said it does not have a specific timeline for its decision.

"Sadly, we're not seeing the urgency that WHO and every other regulator in the planet showed with Covid," Hill said, "which is disappointing, given that there are huge numbers of deaths from malaria in young children in Africa."

The new vaccine could reach more people more quickly

The WHO's recommendation of Mosquirix in 2021 represented a major milestone, but manufacturing challenges have led to a slow rollout.

In 2015, GSK closed the Belgium plant where the vaccine was produced, and it did not reopen until 2019. Last year was the first in which the plant continuously manufactured the vaccine's antigen — the component that stimulates an immune response.

GSK has asked a company in India, Bharat Biotech, to produce the antigen instead, but that won't happen until 2028.

To date, 1.5 million children have received the Mosquirix shot, according to the WHO. In addition to the three countries already administering it, 11 others have applied to receive doses, the WHO said.

"The demand for this vaccine has been unprecedented, with 29 countries already coming forward to Gavi saying that they would like to introduce this vaccine already," Dr. Mary Hamel, the WHO's team lead for malaria vaccines, said on a media call Wednesday. (Gavi is an international vaccine alliance that partners with the WHO, governments and nonprofit groups.)

"Demand far outstrips the supply that's currently available," Hamel added.

GSK said it expects to have around 4 million doses available later this year, and a total of 18 million by the end of 2025.

But the WHO estimates that 80 to 100 million annual vaccine doses are required to immunize children at risk of malaria.

The Oxford vaccine could help alleviate the shortage. The Serum Institute of India has already committed to produce 20 million doses in the next two months. (The company is manufacturing the doses "at risk," meaning it hasn't made a deal with a buyer yet.)

The Oxford shot is also cheaper, at $3 per dose relative to around $10 for the GSK shot.

How do the two malaria shots compare?

Like the Oxford vaccine, Mosquirix consists of four doses. The first three are administered monthly, starting when an infant is 5 months old, followed by the fourth once they reach 15 to 18 months.

In a large-scale trial, three doses of the vaccine reduced the risk of malaria in children by 28% after four years, while four doses had a slightly higher efficacy of 36%.

Hill said the Oxford vaccine's efficacy also wanes over time but was "still very high" after at least 3 1/2 years.

It's possible, though, that the Oxford shot will prove less effective outside of a trial setting, Wirth said, since the study in Burkina Faso largely administered vaccines before the seasonal peak in malaria transmission, which comes in July.

"I expect that, when released at large scale, it will have a similar efficacy to the existing recommended vaccine," she said.

Neither vaccine will eliminate the need for additional measures to keep malaria from spreading, Wirth added.

"Is it a magic bullet? Will the vaccine alleviate the need for bed nets or insecticide spraying? No, definitely not," she said. "The vaccine will also not replace the need for drugs, but it can be added to the existing tools to have greater impact."






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